Preventing heartworm disease involves a multi-faceted approach. Regular veterinary check-ups are crucial for early detection and discussing heartworm preventatives. Limiting outdoor exposure during peak mosquito hours (typically dawn and dusk) and avoiding areas with standing water, or clearing containers that can hold water around your home, can also help. Additionally, using dog-safe mosquito repellent as directed by a vet (never human repellents) can provide an extra layer of protection.